Are prescription or non-prescription allergy medications right for you?

Generally, the difference between prescription and non-prescription allergy medications is the overall time period that the medications work for to eliminate allergy symptoms. Over the counter medicines are generally short acting antihistamines and relieve mild to moderate symptoms; whereas prescription medications are generally longer acting, working for more extended time periods, and may relieve more severe allergy symptoms.

Anaphylaxis, or severe allergic reactions, require a medicine called epinephrine (also referred to as adrenalin), which can potentially be life saving when immediately injected.

Please check each individual specific medication for complete detailed information on side effects, dosage, directions, etc. Please see your physician or health care provider if you experience side effects from any medications you are taking.

Additionally, specific illnesses caused by allergies, such as [asthma] or [eczema], require other treatments and medications. Please see our Key to Understanding Asthma and our Key to Understanding Eczema pages for additional information.

By understanding how allergy medications work, you can be informed when you work with your doctor to develop your treatment plan that will work for you. If you think you might have allergies or are experiencing any allergy symptoms, please your doctor and discuss allergy medication options suitable for you.

Antihistamine Side Effects

Drowsiness and headache are the more common side effects from some antihistamine medications, both over the counter and prescription. However, drowsiness or a slightly sedated feeling may sometimes be desirable, for example at nighttime when allergies could potentially prevent restful sleep.

Less Common side effects include dizziness, dry mouth, nausea, fatigue, and sleepiness.

Rare side effects include rash, hives, anaphylaxis, and shortness of breath.

Other side effects are also possible. If you notice any other effects, please check with your physician or healthcare professional.

Leukotriene modifier side effects

Side effects from leukotriene modifiers include cough, dizziness, headache, stomach upset or pain, stuffy nose, tiredness, or muscle weakness.

Nasal Spray Side Effects

There are some mild nasal spray side effects which may include an unpleasant smell or bitter taste, sneezing, nasal burning or bleeding, runny nose or sore throat, dry mouth, dizziness, drowsiness or fatigue, headache, irritation (especially in the winter), crusting and nose bleeds (especially in the winter).

Eye Drop Side Effects

The side effects of some eye drops may cause burning and stinging when you first apply them, but this usually goes away in a few minutes. Blurred vision and other mild side effects are also possible. Additionally, you may have an increased risk of eye infections, glaucoma and cataracts with prolonged use of eye drops.